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Derived From: Human Cells
Description:
Recombinant Human C-Reactive Protein is produced by Mammalian expression system and the target gene encoding Gln19-Pro224 is expressed with a 6His tag at the C-terminus.
Accession: P02741
Known as: C-Reactive Protein; CRP; PTX1
Quality Control:
Mol Mass: 23.9kDa AP Mol Mass: 24-28kDa, reducing conditions
Purity: Greater than 95% as determined by reducing SDS-PAGE.
Formulation:
Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 280mM NaCl, 5mM CaCl2, pH8.0
Shipping:
The product is shipped on dry ice pack.
Upon receipt, store it immediately at the temperature listed below.
Storage:
Reconstituted protein solution should be stored at ≤ -20°C.
Purification:
Affinity purification chromatography
Application:
Immunogen, calibrator or standard.
Background:
C-reactive protein (CRP) belongs to the pentaxin family. CRP is a secreted protein found in plasma. It can binds two calcium ions per subunit.CRP can promotes phagocytosis, bacterial capsular swelling, complement fixation and agglutination through its calcium-dependent binding to phosphorylcholine which expressed on the surface of dead or dying cells. It can activate the complement system via the C1Q complex. CRP can interact with DNA and histones. In addition, CRP may scavenge nuclear material released from damaged circulating cells.
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