Mol Mass: 13.2kDa    AP Mol Mass: 14kDa, reducing conditions

Purity: Greater than 95% as determined by reducing SDS-PAGE.

Formulation:
Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl,150mM NaCl,1mM EDTA, pH 8.0.

Shipping:

The product is shipped on dry ice pack.Upon receipt, store it immediately at the temperature listed below.

Storage:

Reconstituted protein solution should be stored at  ≤ -20°C.

Purification: 

Affinity purification chromatography

Application:

Immunogen, calibrator or standard.

Background:

Serum Amyloid A1 Protein (SAA1) is an acute phase apolipoprotein reactant that is produced predominantly by hepatocytes and is under the regulation of inflammatory cytokines. SAA is produced mainly in the liver and circulates in low levels in the blood. SAA may play a role in the immune system and facilitate the repair of injured tissues, it also acts as an antibacterial agent, and signals the migration of germ-fighting cells to sites of infection. SAA also functions as an apolipoprotein of the HDL complex. The SAA cleavage product designated amyloid protein A is deposited systemically as amyloid in vital organs such as the liver, spleen, and kidneys in chronic inflammatory diseases patients. These deposits are extremely insoluble and resistant to proteolysis; they disrupt tissue structure and compromise performance.